Exploring the effects of mindfulness meditation on resting-state functional connectivity: an overview.
Reviews in the Neurosciences June 3, 2026 Thomas Le François, Charlotte E Hilberdink, Bérengère Guillery-Girard et al.
Mindfulness meditation training (MMT) can reorganize the brain's functional architecture by altering resting-state functional connectivity (rsFC) within and between the default mode, salience, and central executive networks. Both increases and decreases in rsFC have been observed after MMT, with differential roles in emotion regulation, stress, and cognitive functions. Changes in rsFC after MMT are linked to modifications in cognitive performance and psycho-affective measures, which may be influenced by practice duration or delivery methods. Investigating rsFC in key brain networks during rest is a promising approach to understanding how mindfulness meditation affects overall well-being.