Autoradiographic study on the pharmacological characteristics of [3H]3-OH-PCP binding sites in rat brain.
European Journal of Pharmacology August 29, 1996 T Suzuki, T Yamamoto, T Hori et al.
The pharmacological characteristics and the regional distribution of [3H]3-OH-PCP (1-[1(3-hydroxyphenyl)-cyclohexyl]piperidine) binding were investigated in rat brain by quantitative autoradiography. Kinetic analysis of [3H]3-OH-PCP binding revealed fast and slow components, in the association and dissociation studies. The regional distribution of binding closely corresponded to those of...