Effects of salvinorin A on locomotor sensitization to D2/D3 dopamine agonist quinpirole.
Neuroscience Letters December 3, 2008 Pieter Beerepoot, Vincent M Lam, Alice Luu et al.
Locomotor sensitization induced by the dopamine agonist quinpirole can be potentiated by co-treatment with the synthetic kappa opioid agonist U69593. The identification of salvinorin A, an active component of the psychotropic sage Salvia divinorum, as a structurally different agonist of kappa-opioid receptors raised the question of whether this compound would similarly potentiate sensitization...