Tourette's Syndrome as a vehicle in the search for the neural correlates of consciousness.
Brain and Cognition December 1, 2025 Peter J Chabot, Nicholas B Dadario, Michael E. Sughrue
Brain imaging of people with Tourette's Syndrome who consciously control premonitory urges shows that the non-language dominant prefrontal part of the frontal operculum in the inferior frontal gyrus and the anterior insular cortex are involved in tic inhibition and decision-making. These regions also appear important for intention, volitional control, self-awareness, perception of tangible reality, and attentional selectivity, suggesting they may be part of the neural correlates of consciousness.