Editorial: Incorporating Phase 0 microdosing as a powerful tool into a new vision of drug development
Frontiers in Pharmacology July 16, 2024 H. Markus Weiss, Yuichi Sugiyama, Esther van Duijn
Editorial on the Research Topic Incorporating Phase 0 microdosing as a powerful tool into a new vision of drug developmentPhase 0 microdosing, the testing of compounds at subtherapeutic doses in human to enable early decisions in drug discovery and development has been utilized for some years.The uptake was slow even though the concept is attractive and the pre-clinical safety package enabling...