Classic psychedelics and autism spectrum disorder: preclinical evidence, mechanistic insights and unresolved challenges.
Neuroscience and Biobehavioral Reviews August 1, 2026 Fabrizio Ascone, Diletta Giangiacomo, Viviana Trezza
Classic psychedelics have re-emerged as compelling probes of neural plasticity, raising interest in their potential relevance for behavioral and circuit-level features associated with autism spectrum disorder (ASD). Although only a limited number of studies have examined these compounds in validated animal models of ASD, a growing body of preclinical work has investigated their effects on...