Behavioral effects of orally administered glycine in socially housed monkeys chronically treated with phencyclidine.
Psychopharmacology May 1, 2007 Gary S Linn, Robert T O'Keeffe, Kenneth Lifshitz et al.
Schizophrenia is a major mental disorder. Dissociative anesthetics such as phencyclidine (PCP) produce a syndrome in humans that is clinically indistinguishable from schizophrenia by blocking neurotransmission at N-methyl-D-aspartate (NMDA)-type glutamate receptors. NMDA receptors in brain are modulated by the amino acid glycine (GLY), which reverses neurochemical and behavioral effects of PCP...