Potential benefit of lamotrigine in managing ketamine use disorder.
Medical Hypotheses February 1, 2016 Ming-Chyi Huang, Lian-Yu Chen, Chih-Ken Chen et al.
Ketamine is an anesthetic derivative of phencyclidine (PCP; 'Angel dust') with dissociative, analgesic and psychedelic properties. Ketamine has become a popular recreational drug of abuse in many parts of the world in recent years. The preclinical studies demonstrate the reinforcing effects of ketamine and long-term ketamine abuse induces a delayed and persistent upregulation of dopamine...