Dextromethorphan (DXM) is abused most commonly among adolescents as a recreational drug to generate a dissociative experience. The objective of the study was to assess driving with and without DXM ingestion. The effects of one-time maximum daily doses of DXM 120 mg versus a guaifenesin 400 mg dose were compared among 40 healthy subjects using a crossover design. Subjects' ability to drive was...
A case of prolonged psychotic behavior is described of a 20-year-old female following the ingestion of an illicitly obtained powder probably containing phencyclidine. The various psychiatric manifestations of phencyclidine intoxications are reviewed. The benefit of treating the toxic phase with psychotropic drugs is questionable. Hospitalization, supportive measures and urine acidification...