NMDA receptor antagonists distort visual grouping in rats performing a modified two-choice visual discrimination task.
Psychopharmacology October 1, 2013 Katja Clarissa Ward, Halima Zainab Khattak, Louise Richardson et al.
Visual perception is impaired during pathological psychosis, which can be mimicked by NMDA receptor antagonists. However, the underlying mechanisms are poorly understood, partly due to limits of current rodent models for visual integration. The objectives of the study are (1) to develop a rodent task that can differentiate between effects on perception and nonspecific effects on task...