Hai-Quyen Tran

2 papers in the library · publishing 2018

Papers

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Clozapine attenuates mitochondrial burdens and abnormal behaviors elicited by phencyclidine in mice via inhibition of p47 phox; Possible involvements of phosphoinositide 3-kinase/Akt signaling.

Journal of Psychopharmacology November 2018 Hai-Quyen Tran, Se J Park, Eun-Joo Shin et al.

Oxidative stress and mitochondrial dysfunction have been implicated in the pathophysiology of schizophrenia. We investigated whether antipsychotic clozapine modulates nicotinamide adenine dinucleotide phosphate oxidase and mitochondrial burdens induced by phencyclidine in mice. We examined the effect of clozapine on nicotinamide adenine dinucleotide phosphate oxidase activation, mitochondrial...

DOI: 10.1177/0269881118795244 Full text Clozapine Mitochondria Oxidative stress P47phox knockout mice +3

Blockade of platelet-activating factor receptor attenuates abnormal behaviors induced by phencyclidine in mice through down-regulation of NF-κB.

Brain Research Bulletin March 1, 2018 The-Vinh Tran, Se Jin Park, Eun-Joo Shin et al.

Accumulating evidence suggests that neuroinflammation is one of the important etiologic factors of abusive and neuropsychiatric disorders. Platelet-activating factor (PAF) is potent proinflammatory lipid mediat1or and plays a pivotal role in neuroinflammatory disorders through the specific PAF receptor (PAF-R). Phencyclidine (PCP) induces a psychotomimetic state that closely resembles...

DOI: 10.1016/j.brainresbull.2017.11.004 Full text Phencyclidine Platelet-activating factor receptor Schizophrenia