Inhalational nitrous oxide as a transdiagnostic approach for the treatment of suicidal ideation and suicidality in psychiatric inpatients: protocol for a double-blind randomised, controlled clinical single-centre trial.
BMJ Open July 16, 2025 Golo Kronenberg, Anna Bankwitz, Barbora Provaznikova et al.
Suicidal thoughts and behaviours are linked to a wide range of mental health conditions. New interest in the psychiatric benefits of nitrous oxide (N2O) has only recently emerged. The broad pharmacological effects of N2O are thought to be due in large part to N-methyl-d-aspartate antagonism and opioid effects. The purpose of this study protocol is to test whether inhalational N2O exerts rapid...
DOI: 10.1136/bmjopen-2024-096825 (opens in new tab)
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Clinical pharmacology
Psychometrics
Suicide & self-harm