A study of the role of serotonin in the anxiolytic effect of nitrous oxide in rodents.
Pharmacology, biochemistry, and behavior June 1, 2006 Dimitris E Emmanouil, Z Papadopoulou-Daifoti, Philip T Hagihara et al.
In earlier studies, we have shown that nitrous oxide (N2O)-induced behavioral effects in rats and mice are mediated by benzodiazepine receptors. This two-part study was conducted in order to investigate the possible role of serotonin (5-HT) in the behavioral effects of N2O by clarifying its effects on regional brain concentrations of 5-HT and assessing the influence of 5-HT antagonist and...