The efficacy and tolerability of inhaled nitrous oxide in major depressive disorder: a systematic review and meta-analysis.
Psychopharmacology October 1, 2023 Youjia Qiu, Longyuan Li, Aojie Duan et al.
Nitrous oxide (N2O) has been initially confirmed by clinical trials to benefit to patients with major depressive disorder (MDD). However, there needs to be a meta-analysis to compare the efficacy and tolerability of N2O in MDD. PubMed, EMBASE, and Cochrane Library were searched for relevant studies up to Jan 1st, 2023. The meta-analysis mainly compared the outcome of the change in depression...