Effects of haloperidol on the delta-9-tetrahydrocannabinol response in humans: a responder analysis.
Psychopharmacology September 1, 2019 Swapnil Gupta, Joao P De Aquino, Deepak C D'Souza et al.
Δ-9-Tetrahydrocannabinol (Δ-9-THC) produces psychotomimetic effects in humans. However, the role of dopamine signaling in producing such effects is unclear. We hypothesized that dopaminergic antagonism would reduce the psychotomimetic effect of Δ-9-THC. The objective of this study was to evaluate whether pre-treatment with haloperidol would alter the psychotomimetic and perceptual-altering...
DOI: 10.1007/s00213-019-05235-x (opens in new tab)
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Antipsychotic
Cannabinoid
Dopamine
Haloperidol
+1