Chronic adolescent exposure to cannabis in mice leads to sex-biased changes in gene expression networks across brain regions
Neuropsychopharmacology August 22, 2022 Yanning Zuo, Attilio Iemolo, Patricia Montilla‐Perez et al. 24 citations
During adolescence, frequent and heavy cannabis use can lead to serious adverse health effects and cannabis use disorder (CUD). Rodent models of adolescent exposure to the main psychoactive component of cannabis, delta-9-tetrahydrocannabinol (THC), mimic the behavioral alterations observed in adolescent users. However, the underlying molecular mechanisms remain largely unknown. Here, we treated...