Adolescent THC impacts on mPFC dopamine-mediated cognitive processes in male and female rats.
Psychopharmacology February 1, 2025 Maricela X. Martinez, Vanessa Alizo Vera, Christina M. Ruiz et al. 1 citation
Adolescent cannabis use is linked to later-life changes in cognition, learning, and memory. Rodent experimental studies suggest Δ9-tetrahydrocannabinol (THC) influences development of circuits underlying these processes, especially in the prefrontal cortex, which matures during adolescence. We determined how 14 daily THC injections (5 mg/kg) during adolescence persistently impacts medial...