Gene-environment interaction between an endocannabinoid system genetic polymorphism and cannabis use in first episode of psychosis.
European Neuropsychopharmacology June 1, 2019 M. Bioque, S. Mas, M. Costanzo et al.
Alterations of the endocannabinoid system (ECS) may play an important role in the development of schizophrenia and other psychotic disorders. Cannabis use is one of the environmental factors more repeatedly related to an increase the risk of developing a psychotic episode, while its use modifies the ECS normal function. In the present study we purposed to examine the gene by environment (GxE)...