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J.M.A. Gerven

1 paper in the library · publishing 2025

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Clinical pharmacokinetics of N,N-dimethyltryptamine (DMT): a systematic review and post-hoc analysis

Leiden Repository 2025 Katelijne V. van der Heijden, Marije E. Otto, Jan W. Schoones et al.

BACKGROUND AND OBJECTIVE\nMETHODS\nRESULTS\nCONCLUSION\nN,N-Dimethyltryptamine (DMT) is currently being studied for its therapeutic potential in various psychiatric disorders. An understanding of its pharmacokinetics (PK) is essential to determine appropriate dose ranges in future clinical studies. We conducted a systematic literature review on the PK of DMT.\nClinical studies that administered...

DOI: 10.1007/s40262-024-01450-8#citeas (opens in new tab) Pharmacokinetics Bolus digestion Volume of distribution Dosing +2