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U. Hacksell

1 paper in the library · publishing 1982

Papers

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8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT, a potent and selective simplified ergot congener with central 5-HT-receptor stimulating activity

Journal of Neural Transmission September 1, 1982 S. Hjorth, A. Carlsson, P. Lindberg et al.

It was demonstrated that the simplified ergot congener 8-hydroxy-2-(di-n-propylamino)tetralin, 8-OH-DPAT, is able to elicit pronounced biochemical and behavioural alterations indicative of central serotoninomimetic activity. Since these effects are resistant to prior monoamine depletion and/or synthesis inhibition by means of reserpine and α -propyldopacetamide (H22/54), respectively, they are...

DOI: 10.1007/bf01276574 (opens in new tab) Full text (opens in new tab) 8-hydroxy-2-di-n-propylaminotetralin Ergot congen