Connie Porretta

2 papers in the library · 2 citations · publishing 2015-2016

Papers

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Psychedelics Produce Complex And Heterogeneous Transcriptional Responses In Diverse Cortical Cell Types In The Brain Of Rats As Determined By New Flow Cytometric Methods Allowing For Sorting Of Distinct Cell And Neuronal Populations From Whole Brain

The FASEB Journal April 1, 2016 David Martin, Connie Porretta, Charles D. Nichols 1 citation

Psychedelics, also known as classic serotonin hallucinogens, are currently being investigated by several groups for their potential as therapeutic agents for a variety of psychiatric indications. Although the neural circuitry underlying the effects of psychedelics is being established by others, the role of specific cell types and populations within the brain that respond to these agents remain...

DOI: 10.1096/fasebj.30.1_supplement.930.3 Parvalbumin Cell type Flow cytometry Cerebral cortex +4

Hallucinogens Activate a Specific Population of Neurons in the Cortex

The FASEB Journal April 1, 2015 David Martin, Connie Porretta, Charles D. Nichols 1 citation

Serotonin hallucinogens produce a range of cognitive, sensory, and emotional effects in man. Recently, a resurgence of clinical interest in these compounds has developed because they can produce pronounced and long‐lasting psychological changes. While the structural backbones and receptor pharmacology of hallucinogens vary, their primary effects arise from agonism of the 5‐HT 2A receptor....

DOI: 10.1096/fasebj.29.1_supplement.931.14 Hallucinogen Somatosensory system Population Fosb +5