Effects of the 5-HT2A Agonist Psilocybin on Mismatch Negativity Generation and AX-Continuous Performance Task: Implications for the Neuropharmacology of Cognitive Deficits in Schizophrenia
Neuropsychopharmacology 2003 Daniel Umbricht, Franz X. Vollenweider, Liselotte Schmid et al. 192 citations
Previously the NMDA (N-methyl-D-aspartate) receptor (NMDAR) antagonist ketamine was shown to disrupt generation of the auditory event-related potential (ERP) mismatch negativity (MMN) and the performance of an 'AX'-type continuous performance test (AX-CPT)--measures of auditory and visual context-dependent information processing--in a similar manner as observed in schizophrenia. This...
DOI: 10.1038/sj.npp.1300005 (opens in new tab)
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Psilocybin
Mismatch negativity
Nmda receptor
Schizophrenia object-oriented programming
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