Association Between Lifetime Hallucinogen Use and Valvular Heart Disease: Findings from the All of Us Research Program
Journal of Psychoactive Drugs May 18, 2026 Kevin H. Yang, Miranda Rasmussen, Kush V. Bhatt et al. 1 citation
Recent literature suggests potential associations between hallucinogen use and valvular heart disease (VHD) due to prolonged activation of serotonin 5-HT2B receptors, which may lead to valvular fibrosis – a condition also linked to drugs including fenfluramine and pergolide. Despite these concerns, epidemiological studies exploring this association are lacking. This exploratory analysis...