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Psychedelics in psychiatry: comparative effectiveness, implementation, commercialization and safety lessons learned from intranasal esketamine

Roger S McIntyre

Expert Opinion on Drug Safety August 28, 2026 DOI: 10.1080/14740338.2026.2726227 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Topics Esketamine
Key findings Mental disorders are a leading contributor to the global burden of disease, as measured by disability-adjusted life years, according to the 2023 Global Burden of Diseases study. The authors argue that this burden necessitates greater investment in mental health services and policies.

Abstract

1.0 According to the 2023 iteration of the Global Burden of Diseases, Injuries and Risk Factor studies (GBD) assessing 375 injuries and diseases and 12 mental disorders, mental disorders are now th...