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Pain acceptance as a change mechanism for mindfulness-based cognitive therapy for migraine.

Rachel D Best, Ali Ozmeral, Amy S Grinberg, Todd A Smitherman, Elizabeth K Seng

Journal of behavioral medicine June 1, 2024 DOI: 10.1007/s10865-024-00475-5 (opens in new tab) via PubMed

Summary

AI-generated from the abstract

Pain acceptance, especially the activity engagement component, appears to be a key mechanism by which Mindfulness Based Cognitive Therapy for Migraine (MBCT-M) reduces headache-related disability. In a secondary analysis of a randomized controlled trial with 60 participants, pain acceptance, pain willingness, and activity engagement all increased over time in both the MBCT-M and waitlist/treatment-as-usual groups. Only activity engagement increased more in the MBCT-M group. Changes in pain acceptance, pain willingness, and activity engagement each mediated the relationship between MBCT-M and reduced disability. The findings support the importance of pain acceptance, particularly activity engagement, in MBCT-M.

Study at a glance

Characteristics Secondary analysis of a randomized controlled trial Longitudinal Peer reviewed
Sample size 60
Population Adults with migraine
Intervention Mindfulness Based Cognitive Therapy for Migraine (MBCT-M)
Duration One-month post-treatment, with 6-month follow-up for the MBCT-M group
Topics Meditation
Keywords Disability Migraine Pain acceptance
Key finding Change in pain acceptance, particularly the activity engagement component, mediated the relationship between Mindfulness Based Cognitive Therapy for Migraine and reduced headache-related disability.

Abstract

Migraine is one of the leading causes of disability worldwide. Third wave therapies, such as Mindfulness Based Cognitive Therapy for Migraine (MBCT-M), have proven efficacious in reducing headache-related disability. However, research is needed to better understand the change mechanisms involved in these third-wave therapies. Acceptance is a fundamental component of third wave therapies, and more research is warranted on the role of pain acceptance in MBCT-M. It is also valuable to understand the independent roles of the two components of pain acceptance-pain willingness (PW) and activity engagement (AE). The current study is a secondary analysis of a randomized control trial of MBCT-M. Sixty participants were included in the study (MBCT = 31; WL/TAU = 29). Baseline correlations between overall pain acceptance, PW, AE, and headache-related disability were run. Mixed models assessed change from baseline to one-month post-treatment and treatment-by-time interaction for overall pain acceptance, PW, and AE. Mixed models also assessed maintenance of changes at 6-month follow-up in the MBCT-M group. Longitudinal mediation models assessed whether change in pain acceptance, PW, and AE mediated the relationship between treatment and change in headache-related disability. Pain acceptance, PW, and AE were all negatively correlated with headache-related disability at baseline. Pain acceptance, PW, and AE all significantly increased over time in both the waitlist/ treatment-as-usual group (WL/TAU) and the MBCT-M group. Only AE increased more in the MBCT group than the WL/TAU group. Change in pain acceptance, PW, and AE all significantly mediated the relationship between MBCT and change in headache-related disability. The study supports the importance of pain acceptance, specifically the activity engagement component, in MBCT-M.

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