Blinding, Expectancy, and the Active Placebo Paradox in MDMA Research.
Psychopharmacology (Berl) June 13, 2026 DOI: 10.1007/s00213-026-07108-6 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper Peer reviewed |
|---|---|
| Topics | MDMA |
| Key points | Argues that the active placebo paradox—where MDMA's strong subjective effects compromise blinding—challenges the validity of standard placebo-controlled trials and requires alternative methodological designs. |
Abstract
Blinding, Expectancy, and the Active Placebo Paradox in MDMA Research.