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Acute suicidal behavior following ayahuasca ingestion in a clinical trial setting: a case report.

José Augusto S. Reis, Giordano N. Rossi, Anna Beatriz V. Zacharias, Jaime E. C. Hallak, Rafael G. Dos Santos

Braz J Psychiatry September 29, 2025 DOI: 10.47626/1516-4446-2025-4354 (opens in new tab) via PubMed

Summary

AI-generated from the abstract

A case report describes an instance of acute suicidal behavior that occurred after a participant ingested ayahuasca in a clinical trial setting. The report details the circumstances and clinical presentation of this adverse event, highlighting a potential risk associated with ayahuasca use even within a controlled research environment. The authors suggest that such reactions, though rare, warrant careful screening and monitoring of participants in psychedelic research.

Study at a glance

Characteristics Case report Peer reviewed
Sample size 1
Population A participant in a clinical trial who ingested ayahuasca
Intervention Ayahuasca
Key finding Acute suicidal behavior occurred after ayahuasca ingestion in a clinical trial setting.

Abstract

Acute suicidal behavior following ayahuasca ingestion in a clinical trial setting: a case report.

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