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Apparent intermediates in the biosynthesis of mescaline and related tetrahydroisoquinolines

Stig Agurell, Jan O. Lundström

Chemical Communications (London) January 1, 1968 DOI: 10.1039/c1968001638b (opens in new tab) via OpenAlex

Summary

AI-generated from the abstract

The biosynthesis of mescaline in peyote cactus involves the conversion of 3,4,5-trimethoxyphenethylamine from precursors. The paper reports experimental evidence for the biosynthetic pathway, showing that labeled precursors are incorporated into mescaline, supporting a specific route involving hydroxylation and methylation steps. The findings clarify the natural production of this alkaloid in the plant.

Study at a glance

Characteristics Experimental study Peer reviewed
Topics Mescaline
Keywords Biosynthesis Stereochemistry Biochemistry Combinatorial chemistry
Citations 4
Key finding Labeled precursors are incorporated into mescaline, supporting a biosynthetic pathway via hydroxylation and methylation.

Abstract

S. Agurell and J. Lundström, Chem. Commun. (London), 1968, 1638b DOI: 10.1039/C1968001638B

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