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Development and application of a highly sensitive LC-MS/MS method for simultaneous quantification of N,N-dimethyltryptamine and two of its metabolites in human plasma.

Emma Eckernäs, Adam Bendrioua, Chiara Cancellerini, Christopher Timmermann, Robin Carhart-Harris, Kurt-Jürgen Hoffmann, Michael Ashton

J Pharm Biomed Anal February 3, 2022 DOI: 10.1016/j.jpba.2022.114642 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Method development and validation Peer reviewed
Topics 5-MeO-DMT DMT
Keywords DMT Research DMT Natural compounds Substances DMT'S Effects DMT'S Metabolism Analytical method method Technology Instrument Quantifies Highly sensitive method Precisely measure Robust tool New method Breakdown products
Citations 18
Key points A highly sensitive LC-MS/MS method was developed and applied for simultaneous quantification of DMT and two of its metabolites in human plasma.

Abstract

Development and application of a highly sensitive LC-MS/MS method for simultaneous quantification of N,N-dimethyltryptamine and two of its metabolites in human plasma.