Cross-species metabolic characterization of eutylone and mechanism-based inhibition of CYP2D6 and CYP2B6 with drug interaction implications.
Scientific Reports April 16, 2026 Min Seo Lee, Im-Sook Song, Yeonsu Jang et al.
Eutylone is a methylenedioxy-substituted synthetic cathinone increasingly detected in toxicological case analyses and commonly encountered under polydrug use conditions. To support metabolism-informed surveillance and risk assessment of emerging stimulants, this study comprehensively characterized eutylone disposition and interaction liability using plasma protein binding, metabolic stability...