Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder.
Cochrane Database of Systematic Reviews October 8, 2021 Rebecca L. Dean, Tahnee Marquardt, Claudia C. Hurducas et al. 41 citations
BACKGROUND Glutamergic system dysfunction has been implicated in the pathophysiology of bipolar depression. This is an update of the 2015 Cochrane Review for the use of glutamate receptor modulators for depression in bipolar disorder. OBJECTIVES 1. To assess the effects of ketamine and other glutamate receptor modulators in alleviating the acute symptoms of depression in people with bipolar...