Impact of Formulation Variables on the Quality Attributes of Psilocybin-Loaded Oral Thin Films for Early-Phase Development
Journal of Drug Delivery Science and Technology March 1, 2026 Vorawut Wongumpornpinit, K Ingkaninan, Prapapan Temkitthawon et al.
Psilocybin is an emerging investigational compound with therapeutic potential in neuropsychiatric disorders, creating a need for flexible and scalable dosage forms suitable for early clinical development. This study aimed to develop and evaluate psilocybin-loaded oral thin film (OTF) formulations as a dose-proportional platform for early-phase clinical use. OTFs were prepared using a solvent...