Ketamine-induced prevention of SD-associated late infarct progression in experimental ischemia.
Scientific Reports May 3, 2024 A Zdunczyk, L Schumm, S O A Helgers et al. 5 citations
Spreading depolarizations (SDs) occur frequently in patients with malignant hemispheric stroke. In animal-based experiments, SDs have been shown to cause secondary neuronal damage and infarct expansion during the initial period of infarct progression. In contrast, the influence of SDs during the delayed period is not well characterized yet. Here, we analyzed the impact of SDs in the delayed...