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P. Louzada-Júnior

2 papers in the library · publishing 2022-2023

Papers

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Effect of D2R, NMDAR and CB1R genetic variants associated with cannabis use and childhood trauma in first-episode psychosis in a Brazilian population

European Psychiatry March 1, 2023 C. Loureiro, F. Corsi-Zuelli, H. Fachim et al.

Introduction Gene-environment interactions increase psychosis risk (Gayer-Anderson et al. Soc Psychiatry Psychiatr Epidemiol 2020; 55(5):645-657). However, identifying the genetic variants involved and how they interact with environmental risk factors underlying psychosis remains challenging. Objectives To investigate whether there are gene-environment interactions in the relationships of...

Immune regulatory gene polymorphisms, frequent cannabis use, and psychosis: implications to Treg hypofunction

European Psychiatry June 1, 2022 F. Corsi-Zuelli, C. Loureiro, R. Shuhama et al.

Introduction We have previously shown that the association between frequent cannabis use and psychosis is more likely in subgroups with low-grade inflammation than subgroups without (PMID: 33736715). The role of immune-related polymorphisms remains unknown. Objectives To explore whether polymorphisms affecting the function of key immune regulatory proteins moderate the association between...