Dextromethorphan-induced serotonin syndrome leading to rhabdomyolysis and dialysis-requiring acute kidney injury: a case report and review
Renal Replacement Therapy April 15, 2025 Kazuhiro Okamoto, Nobuhiro Hashimoto, Kaiya Ishizeki et al.
Dextromethorphan (DXM) misuse, particularly among young individuals, has risen owing to its euphoric and hallucinogenic effects. High-dose DXM ingestion can trigger serotonin syndrome, a condition characterized by psychiatric, neuromuscular, and autonomic symptoms. In severe cases, serotonin syndrome may result in rhabdomyolysis and acute kidney injury (AKI). However, reports of severe...