Recalibrating Pain–Mood Coupling in Fibromyalgia: A Hypothesis-Generating Multisystem Neurobehavioral Framework for Mindfulness-Based Interventions
Anesthesia Research September 13, 2026 Camilla Teixeira Pinheiro Gusmão, Batuhan Özen, Marina Seixas Studart E Neves et al.
Background/Objectives: Fibromyalgia (FM) is a nociplastic pain syndrome characterized by chronic widespread pain, fatigue, sleep disturbance, cognitive dysfunction, and heightened sensitivity to somatic and environmental stimuli. Depressive symptoms and major depressive disorder (MDD) frequently co-occur with FM and are associated with greater disability, pain catastrophizing, sleep disruption,...