Acute lysergic acid diethylamide induces a time-dependent shift toward hippocampal control of default mode network reorganization
Fahd François Hilal, Rayane Benkeddada, Jeanblanc Jérôme et al.
Background Classical psychedelics induce profound changes in brain function, yet the temporal organization of these effects remains incompletely understood. Methods We investigated the effects of acute lysergic acid diethylamide (LSD) on large-scale brain connectivity in nine male Long–Evans rats using resting-state functional magnetic resonance imaging. Following a 15-min baseline acquisition,...