Ketamine retards recovery from reward downshift and supports conditioned taste aversion.
Pharmacology, biochemistry, and behavior October 28, 2023 Antonio D R Agüera, Clara Cándido, Rocío Donaire et al. 4 citations
Ketamine is a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist with antidepressant, anxiolytic, and memory effects in clinical and preclinical studies. The present studies investigated the behavioral effects of ketamine in animals exposed to a consummatory successive negative contrast (cSNC) task involving unexpected reward downshift, negative emotion (frustration), and aversive...