Safety and efficacy of ketamine use in patients with vaso-occlusive crisis: A systematic review and meta-analysis.
EJHaem December 1, 2024 Ernesto Calderon Martinez, Stephin Zachariah Saji, Thomas Campos Carmona et al. 2 citations
Sickle cell disease (SCD) is characterized by acute episodes called vaso-occlusive crises (VOC). VOC is marked by severe pain due to blocked blood vessels by sickled cells. Ketamine has been reported to be effective and safe in managing VOC in SCD patients. This review aims to determine ketamine's safety and efficacy through analysis of clinical trials and observational studies. Adhering to...