A fatal poisoning involving 25C-NBOMe.
Forensic Science International June 1, 2015 Mette Findal Andreasen, Rasmus Telving, Ingrid Rosendal et al.
A young male died approximately 12 hours after recreational use of the potent hallucinogenic drug 25C-NBOMe, with signs of serotonin toxicity before death. Toxicological analysis of blood, urine, vitreous humor, liver, and gastric content samples using UPLC-HRTOF-MS and UPLC-MS/MS identified and quantified 25C-NBOMe and a demethylated and glucuronidated metabolite. Concentrations ranged from 0.32 μg total in gastric content to 2.93 μg/kg in urine. Autopsy findings were consistent with acute poisoning. The cause of death was a fatal overdose of 25C-NBOMe combined with amphetamine. This is the first reported quantification of 25C-NBOMe in biological specimens from a fatal intoxication.