Functional imaging evidence for task-induced deactivation and disconnection of a major default mode network hub in the mouse brain
Proceedings of the National Academy of Sciences of the United States of America June 15, 2020 J. Ferrier, E. Tiran, T. Deffieux et al.
Significance Our report first validates an imaging technique, functional ultrasound, an experimental approach providing significantly higher sensitivity and spatiotemporal resolution than fMRI, for the study of sensory stimulation-induced changes in activation and connectivity patterns in the awake mouse brain. Next, by using this approach in lightly sedated conscious mice, we provide...