Cytotoxic Effects of the Synthetic Cannabinoid, 5F-MDMB-PICA on Human Glioblastoma U87-MG Cells.
International journal of medical sciences 2026 Mohammed Mufadhe Alanazi, Fawaz Alasmari, Mohammad M Algahtani et al.
Synthetic cannabinoids, particularly 5F-MDMB-PICA, have emerged as potent psychoactive substances, exhibiting a binding affinity to the CB1 receptor approximately 380 times greater than that of Δ9-THC, the principal psychoactive compound in cannabis. Their widespread abuse has been associated with severe intoxication and fatalities globally. This study aimed to investigate the cytotoxic effects...